MBCL-13. COMBINED MULTIPLE CHEMOTHERAPY AND POSTERIOR FOSSA RADIOTHERAPY IN INFANTS WITH NONMETASTATIC MEDULLOBLASTOMA

Combined irradiation and chemotherapy using ifosfamide, cisplatin, and etoposide for children with medulloblastoma/posterior fossa primitive neuroectodermal tumor--results of a pilot study.

Ten children with newly diagnosed medulloblastoma/primitive neuroectodermal tumor of the posterior fossa were treated with total surgical resection, radiation therapy, and ICE chemotherapy regimen with ifosfamide (900 mg/m2, days 1-5), cisplatin (20 mg/m2, days 1-5), and etoposide (60 mg/m2, days 1-5) every 4 weeks for eight cycles. Four children under 2 years old were at first treated with eig...

Morbidity of combined chemotherapy and radiotherapy

Treatment of adult nonmetastatic medulloblastoma patients according to the paediatric HIT 2000 protocol: a prospective observational multicentre study.

BACKGROUND Medulloblastoma in adulthood is rare. Knowledge is limited, and the efficacy and toxicity of chemotherapy--especially in nonmetastatic disease--is still elusive. METHODS Seventy adults aged ≥21 years (median age: 28.5 years) with nonmetastatic medulloblastoma were followed as observational patients within the prospective paediatric multicentre trial HIT 2000. Treatment consisted of...

comparison of blood flow velocity changes in posterior cerebral artery measured with transcranial doppler sonography in migraineurs with visual aura and normal persons after photostimulation

چکیده ندارد.

Adult neuroectodermal tumours of posterior fossa (Medulloblastoma) and of supratentorial sites

1.1.1 definition Medulloblastoma is a highly cellular malignant embryonal neoplasm classified as a Primitive Neuroectodermal Tumour (PNET) (Kleihues 1993). It is the most common malignant brain tumour in childhood, accounting for between 15 and 25 % of all childhood primary central nervous system (CNS) neoplasms (Peris-Bonet 2006). By definition, medulloblastoma arises in the posterior fossa, u...